Mono Junior Year Sem 1

Yes and no. I totally recommend, if you can, signing up for online JC classes to get a more impressive array of transcripts for high school and college classes. It will show you are locking in and will be a good student in college. While it may hinder your GPA and will appear as a drop in your college apps, you can explain how mono affected you, and how you've strived to work harder to still be worth their time. I'd recommend starting an academic-based club to show you want more rigorous classes. Maybe it's an Advanced US history club where the club talks more deeply about the subject (if so, I can provide some sources to look into) or an Advanced english or math club. Best of luck and I strongly think you'll get into your dream colleges with how driven you are!

Just explain well on the college essays bro, cuz if you have understandable reason, then it's fine

I'd check if you can take them over the summer, but at my school I was able to take AP Calc over the summer to be able to take multivariable senior year if taking APs is a need for you. Best thing you can do is just concentrating on building good grades and building a well rounded essay. I'd try using the calculators on college vine too to see your acceptance chances, as its your whole application that matters.