How would withdrawing from a class look?

I wouldn't worry about it. My guess was that it was hard to focus on this difficult subject during a pandemic. I imagine you still want to take Calc 2 so just re-apply and get a good grade next try. I advise you to do it over this summer when there will be less school pressure.

Hello, I am impressed that you took Calc 2 as a sophomore. I am a junior currently taking Calc 1 (dual enrollment). I almost had to withdraw but my advisor convinced me to stay in recently. First of all, the admissions office will be impressed because not a lot of people would say they took Calc 2 as a sophomore in high school. Calc 2 is a very hard class. I recommend taking it again next semester (if it is part of your course plan) and do better on it. It will show improvement which is what they are looking for. I hope this helps!

I don't think it would matter very much unless you have withdrawn from lot's of other classes. Otherwise, don't worry about it!

Well, there is no point worrying about it now since you already withdrew. Focus on things that you can do now (extracurriculars, this semester's courses, clubs, organizations, etc) to help improve you application and make yourself look as best as possible.

To answer your questions directly though - it depends. Are you applying to a large, not-so-selective state school or the Ivy Leagues? What other courses are you taking? Are you a STEM major not? Did you take AP Calculus BC (similar to Calc 2 at school)? There are so many other questions and things to be factored. Ultimately, I would not worry about it and focus on the things that can be improved.

Potentially suspicious, maybe? It depends on your other qualifications. How rigorous is your transcript? What other classes are you taking? Most importantly, why did you withdraw? After you withdrew, what did you take instead and why?